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Sargachromenol Isolated from <i>Sargassum horneri</i> Attenuates Glutamate-Induced Neuronal Cell Death and Oxidative Stress through Inhibition of MAPK/NF-κB and Activation of Nrf2/HO-1 Signaling Pathway

Oxidative stress-induced neuronal cell loss is considered to be the major mechanism underlying the pathogenesis of neurodegenerative diseases, which could be induced by a high concentration of glutamate. In this study, sargachromenol (SC) was isolated from a marine brown seaweed <i>Sargassum horneri...

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Principais autores: Eui-Jeong Han, Chunying Zhang, Hyun-Soo Kim, Ji-Yul Kim, Sang-Muyn Park, Won-Kyo Jung, Ginnae Ahn, Seon-Heui Cha
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-11-01
Serier:Marine Drugs
Fag:
sargachromenol
<i>Sargassum horneri</i>
Neuroprotective effects
oxidative stress
neurons cell death
glutamate
Online adgang:https://www.mdpi.com/1660-3397/20/11/710
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