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Biochemical characterization of the Nocardia lactamdurans ACV synthetase.

The L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase (ACVS) is a nonribosomal peptide synthetase (NRPS) that fulfills a crucial role in the synthesis of β-lactams. Although some of the enzymological aspects of this enzyme have been elucidated, its large size, at over 400 kDa, has hampered hetero...

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Autors principals: Riccardo Iacovelli, Reto D Zwahlen, Roel A L Bovenberg, Arnold J M Driessen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2020-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0231290
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