Priming as a strategy to overcome detrimental pH effects on cells for intervertebral disc regeneration

Disc disease is characterised by degeneration of the nucleus pulposus (NP), the central gelatinous tissue of the intervertebral disc (IVD). As degeneration progresses, the microenvironment of the IVD becomes more hostile (i.e. decrease in oxygen, glucose and pH), providing a significant challenge fo...

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Bibliografski detalji

Glavni autori:	J Gansau, CT Buckley
Format:	Artigo
Jezik:	Inglês
Izdano:	Forum Multimedia Publishing LLC 2021-02-01
Serija:	European Cells & Materials
Teme:	acid-sensing ion channel articular chondrocytes bone-marrow-derived stem cells hydrogel metabolism nucleus pulposus pre-culture transforming growth factor β3
Online pristup:	https://www.ecmjournal.org/papers/vol041/pdf/v041a11.pdf
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