The emerging roles of CDK12 in tumorigenesis
Abstract Cyclin-dependent kinases (CDKs) are key regulators of both cell cycle progression and transcription. Since dysregulation of CDKs is a frequently occurring event driving tumorigenesis, CDKs have been tested extensively as targets for cancer therapy. Cyclin-dependent kinase 12 (CDK12) is a tr...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2017-10-01
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| coleção: | Cell Division |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13008-017-0033-x |
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