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Exploring the dynamics of adult Axin2 cell lineage integration into dentate gyrus granule neurons

The Wnt pathway plays critical roles in neurogenesis. The expression of Axin2 is induced by Wnt/β-catenin signaling, making this gene a reliable indicator of canonical Wnt activity. We employed pulse-chase genetic lineage tracing with the Axin2-CreERT2 allele to follow the fate of Axin2+ lineage in...

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Tallennettuna:
Päätekijät: Khadijeh A. Sharifi, Faraz Farzad, Sauson Soldozy, Matthew R. DeWitt, Richard J. Price, Jason Sheehan, M. Yashar S. Kalani, Petr Tvrdik
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2024-02-01
Sarja:Frontiers in Neuroscience
Aiheet:
adult neurogenesis
dentate gyrus
Wnt signaling
Axin2 cell lineage
focused ultrasound
Linkit:https://www.frontiersin.org/articles/10.3389/fnins.2024.1353142/full
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