Exploring the dynamics of adult Axin2 cell lineage integration into dentate gyrus granule neurons

The Wnt pathway plays critical roles in neurogenesis. The expression of Axin2 is induced by Wnt/β-catenin signaling, making this gene a reliable indicator of canonical Wnt activity. We employed pulse-chase genetic lineage tracing with the Axin2-CreERT2 allele to follow the fate of Axin2+ lineage in...

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Auteurs principaux:	Khadijeh A. Sharifi, Faraz Farzad, Sauson Soldozy, Matthew R. DeWitt, Richard J. Price, Jason Sheehan, M. Yashar S. Kalani, Petr Tvrdik
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-02-01
Collection:	Frontiers in Neuroscience
Sujets:	adult neurogenesis dentate gyrus Wnt signaling Axin2 cell lineage focused ultrasound
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1353142/full
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