Locus coeruleus integrity and left frontoparietal connectivity provide resilience against attentional decline in preclinical alzheimer’s disease

Abstract Background Autopsy work reported that neuronal density in the locus coeruleus (LC) provides neural reserve against cognitive decline in dementia. Recent neuroimaging and pharmacological studies reported that left frontoparietal network functional connectivity (LFPN-FC) confers resilience ag...

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Bibliographic Details

Main Authors:	Jennifer Pahl, Prokopis C. Prokopiou, Elisenda Bueichekú, Aaron P. Schultz, Kathryn V. Papp, Michelle E. Farrell, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I.L. Jacobs
Format:	Artigo
Language:	Inglês
Published:	BMC 2024-05-01
Series:	Alzheimer’s Research & Therapy
Subjects:	Alzheimer’s disease Amyloid Attention Cognitive decline Left frontoparietal network Locus coeruleus
Online Access:	https://doi.org/10.1186/s13195-024-01485-w
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