Tetrabenazine Mitigates Aberrant Release and Clearance of Dopamine in the Nigrostriatal System, and Alleviates L-DOPA-Induced Dyskinesia in a Mouse Model of Parkinson’s Disease
Background: L-DOPA-induced dyskinesia (LID), occurring with aberrant processing of exogenous L-DOPA in the dopamine-denervated striatum, is a main complication of levodopa treatment in Parkinson’s disease. Objective: To characterize the effects of the vesicular antagonist tetrabenazine (TBZ) on L-DO...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SAGE Publishing
2022-07-01
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| Col·lecció: | Journal of Parkinson’s Disease |
| Accés en línia: | https://doi.org/10.3233/JPD-223195 |
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