Acylhydrazone derivatives of barbituric acid: Synthesis, in vitro α-amylase inhibition, molecular docking, ADMET and DFT analysis
In this study, a new series of acylhydrazones of barbituric acid were successfully synthesized and characterized through mass, 1H and 13C NMR spectroscopy. The compounds (4a-f) were assessed for their in vitro α-amylase inhibitory activity, showing potent inhibition with IC50 values ranging from 2.4...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2025-09-01
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| Seri Bilgileri: | Results in Chemistry |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2211715625006344 |
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