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Discovery and development of natural heat shock protein 90 inhibitors in cancer treatment

Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone that plays a vital role in the signal transduction of cancers. Hsp90 inhibitors are able to inhibit Hsp90 or the complex of Hsp90 and co-chaperones resulting in the degradation of Hsp90-dependent client proteins through the ubiq...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yong Li, Dongmei Zhang, Jun Xu, Junmin Shi, Lei Jiang, Nan Yao, Wencai Ye
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2012-06-01
Rangatū:Acta Pharmaceutica Sinica B
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211383512000639
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