RU.521 protects against neutrophil extracellular traps-induced vascular endothelial injury by inhibiting cGAS/STING pathway

This study aims to investigate the effect of RU.521 on improving vascular endothelial injury in 14 acute lung injury patients. Serum myeloperoxidase, double-stranded DNA (dsDNA), IFN-β, and TNF-α levels of patients were detected by ELISA. Neutrophil extracellular traps were used to stimulate human...

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Hlavní autoři:	Biao Zhang, Zaojun Fang, Ying Lin, Qian Wu, Jiaping Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Bangladesh Pharmacological Society 2024-06-01
Edice:	Bangladesh Journal of Pharmacology
Témata:	RU.521; Vascular endothelial injury; Neutrophil extracellular traps Western blot
On-line přístup:	https://www.banglajol.info/index.php/BJP/article/view/72930
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