RU.521 protects against neutrophil extracellular traps-induced vascular endothelial injury by inhibiting cGAS/STING pathway

This study aims to investigate the effect of RU.521 on improving vascular endothelial injury in 14 acute lung injury patients. Serum myeloperoxidase, double-stranded DNA (dsDNA), IFN-β, and TNF-α levels of patients were detected by ELISA. Neutrophil extracellular traps were used to stimulate human...

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Autores principales:	Biao Zhang, Zaojun Fang, Ying Lin, Qian Wu, Jiaping Chen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Bangladesh Pharmacological Society 2024-06-01
Colección:	Bangladesh Journal of Pharmacology
Materias:	RU.521; Vascular endothelial injury; Neutrophil extracellular traps Western blot
Acceso en línea:	https://www.banglajol.info/index.php/BJP/article/view/72930
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