Tri-valorization of methanol in a single bioreactor: co-production of enzyme, chemical, and single-cell protein using engineered Pichia pastoris (Komagataella phaffii)

Abstract The economic viability of methanol-based biomanufacturing, particularly with green methanol as feedstock, is often limited by the low value of single-product processes. Here, we developed an integrated co-production strategy in the methylotrophic yeast Pichia pastoris (Komagataella phaffii)...

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Principais autores:	Jiayu Fang, Shuxian Wang, Guoxia Liu, Yanping Zhang, Yin Li, Taicheng Zhu
Format:	Artigo
Jezik:	Inglês
Izdano:	SpringerOpen 2026-07-01
Serija:	Bioresources and Bioprocessing
Teme:	Pichia pastoris (Komagataella phaffii) Methanol feedstock Co-production strategy Single-cell protein Industrial enzymes Erythritol
Online dostop:	https://doi.org/10.1186/s40643-026-01099-0
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