Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Abstract Inflammatory bowel diseases (IBD) affect over 6 million people globally and current treatments achieve only 10‐20% rates of durable disease remission. Bacterial extracellular vesicles (BEVs) from probiotic lactic acid bacteria (LAB) are a promising novel therapeutic with mechanisms holding...

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Egile Nagusiak:	Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Wiley 2026-02-01
Saila:	Advanced Science
Gaiak:	bacterial membrane vesicles colitis extracellular vesicles IBD lactic acid bacteria
Sarrera elektronikoa:	https://doi.org/10.1002/advs.202512679
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