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Multi-trait genetic analysis of asthma and eosinophils uncovers pleiotropic loci in East Asians

Abstract Asthma is a prevalent respiratory condition with over 100 genetic loci identified through genome-wide association studies (GWAS). However, the genetic basis of asthma in East Asians remains underexplored. To address this, we performed a comprehensive analysis of shared genetic mechanisms be...

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書誌詳細
主要な著者: Lili Zhi, Qiwen Zheng, Yue Jiang, Lu Yu, Linzehao Li, Yingchao Song, Bichen Peng, Chumeng Zhang, Hengxuan Jiang, Ren Li, Frank Mentch, Joseph Glessner, Peilin Jia, Hua Tang, Hakon Hakonarson, Xiao Chang
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2025-05-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-025-60405-0
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