Multi-trait genetic analysis of asthma and eosinophils uncovers pleiotropic loci in East Asians

Abstract Asthma is a prevalent respiratory condition with over 100 genetic loci identified through genome-wide association studies (GWAS). However, the genetic basis of asthma in East Asians remains underexplored. To address this, we performed a comprehensive analysis of shared genetic mechanisms be...

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Autori principali:	Lili Zhi, Qiwen Zheng, Yue Jiang, Lu Yu, Linzehao Li, Yingchao Song, Bichen Peng, Chumeng Zhang, Hengxuan Jiang, Ren Li, Frank Mentch, Joseph Glessner, Peilin Jia, Hua Tang, Hakon Hakonarson, Xiao Chang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-05-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-025-60405-0
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