Organophosphorus S-adenosyl-L-methionine mimetics: synthesis, stability, and substrate properties

S-Adenosyl-l-methionine (SAM)-mediated methylation of biomolecules controls their function and regulates numerous vital intracellular processes. Analogs of SAM with a reporter group in place of the S-methyl group are widely used to study these processes. However, many of these analogs are chemically...

Description complète

Détails bibliographiques

Auteurs principaux:	Alexander Yu Rudenko, Sofia S. Mariasina, Anastasiia K. Bolikhova, Maxim V. Nikulin, Ratislav M. Ozhiganov, Vasiliy G. Vasil’ev, Yuri A. Ikhalaynen, Anastasia L. Khandazhinskaya, Maxim A. Khomutov, Peter V. Sergiev, Alex R. Khomutov, Vladimir I. Polshakov
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-08-01
Collection:	Frontiers in Chemistry
Sujets:	S-adenosyl-L-methionine SAM analogs halide methyltransferase MAT2A COMT WBSCR27
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fchem.2024.1448747/full
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!