TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING
Trastuzumab-deruxtecan (T-DXd) is a clinically effective antibody–drug conjugate (ADC) for HER2+ and HER2-low breast cancers, yet its intracellular mechanisms remain elusive. We used a multimodal imaging approach including confocal, immuno-EM, and biochemical assays to investigate T-DXd dynamics in...
محفوظ في:
| التنسيق: | Artigo |
|---|---|
| اللغة: | Inglês |
| منشور في: |
PAGEPress Publications
2025-08-01
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| سلاسل: | European Journal of Histochemistry |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://www.ejh.it/ejh/article/view/4305 |
| الوسوم: |
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