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Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

In Thermus thermophilus, an aerobic Gram‐negative eubacterium used as a model organism, more than half of the phosphorylation sites identified by proteomic analysis are located near the ligand‐binding site, including the active site, of the enzyme in the three‐dimensional structure. We investigated...

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Principais autores: Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2025-12-01
Series:FEBS Open Bio
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Acceso en liña:https://doi.org/10.1002/2211-5463.70103
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