Impairment of TrkB-PSD-95 signaling in Angelman syndrome.
Angelman syndrome (AS) is a neurodevelopment disorder characterized by severe cognitive impairment and a high rate of autism. AS is caused by disrupted neuronal expression of the maternally inherited Ube3A ubiquitin protein ligase, required for the proteasomal degradation of proteins implicated in s...
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| المؤلفون الرئيسيون: | , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science (PLoS)
2013-01-01
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| سلاسل: | PLoS Biology |
| الوصول للمادة أونلاين: | http://europepmc.org/articles/PMC3570550?pdf=render |
| الوسوم: |
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