Colony-Stimulating Factor-1 Receptor Inhibition Transiently Attenuated the Peripheral Immune Response to Experimental Traumatic Brain Injury

To investigate microglial mechanisms in central and peripheral inflammation after experimental traumatic brain injury (TBI), we inhibited the colony-stimulating factor-1 receptor (CSF-1R) with PLX5622 (PLX). We hypothesized that microglia depletion would attenuate central inflammation acutely with n...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Katherine R. Giordano, Maha Saber, Tabitha R.F. Green, Luisa M. Rojas-Valencia, J. Bryce Ortiz, Sean M. Murphy, Jonathan Lifshitz, Rachel K. Rowe
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	SAGE Publishing 2023-04-01
Σειρά:	Neurotrauma Reports
Θέματα:	concussion inflammation microglia peripheral immune response PLX
Διαθέσιμο Online:	https://www.liebertpub.com/doi/full/10.1089/NEUR.2022.0092
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