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Comparison of the basic morphology and function of 3D lung epithelial cultures derived from several donors

In vitro models of the human lung play an essential role in evaluating the toxicity of inhaled compounds and understanding the development of respiratory diseases. Three-dimensional (3D) organotypic models derived from lung basal epithelial cells and grown at the air–liquid interface resemble human...

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Principais autores: David Bovard, Albert Giralt, Keyur Trivedi, Laurent Neau, Petros Kanellos, Anita Iskandar, Athanasios Kondylis, Karsta Luettich, Stefan Frentzel, Julia Hoeng, Manuel C. Peitsch
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-06-01
coleção:Current Research in Toxicology
Assuntos:
Organotypic
Donor variability
Bronchial culture
Small airway culture
Lung toxicology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666027X20300104
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