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A Statistical Approach for Comparative Assessment of the Effect of Smoke Exposure in In Vivo Experiments: A Case Study of an OECD 90-Day Inhalation Study Including 3R4F and 1R6F Reference Cigarettes

In vivo testing is a crucial part of product development. Most in vivo toxicology studies are conducted in a heavily regulated environment, in accordance with sound scientific principles, and in an ethical manner. Statistical methods are an important component of these scientific principles, and man...

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Autores principales: Kondylis Athanasios, Kogel Ulrike, Ho Jenny, Wong EeTsin, Phillips Blaine, Hoeng Julia, Vanscheeuwijck Patrick
Formato: Artigo
Lenguaje:Inglês
Publicado: Sciendo 2025-01-01
Colección:Contributions to Tobacco and Nicotine Research
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Acceso en línea:https://doi.org/10.2478/cttr-2025-0003
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