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Synaptic mitochondrial dysfunction and Alzheimer’s disease: from molecular mechanisms to therapeutic strategies

The ability of AD treatments targeting classic pathological proteins to achieve meaningful clinical outcomes has been severely limited, shifting attention to the earlier upstream pathways that drive disease progression. Increasing evidence indicates that synaptic mitochondrial dysfunction is an earl...

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Autors principals: Yuxin Wang, Weidong Wu, Lishuang Yan, Bo Zhang, Quan Li, Yanyan Zhou
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2026-09-01
Col·lecció:Frontiers in Pharmacology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fphar.2026.1849218/full
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