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Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

<p>Abstract</p> <p>Background</p> <p>Post-transcriptional gene silencing (PTGS) by short interfering RNA has opened up new directions in the phenotypic mutation of cellular genes. However, its efficacy on non-nuclear genes and its effect on the interferon pathway remain unexplored. Since directed mu...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Barik Sailen, Bitko Vira
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2001-12-01
Sarja:BMC Microbiology
Linkit:http://www.biomedcentral.com/1471-2180/1/34
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