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Optimized RNA interference therapeutics combined with interleukin-2 mRNA for treating hepatitis B virus infection

Abstract This study aimed to develop a pan-genotypic and multifunctional small interfering RNA (siRNA) against hepatitis B virus (HBV) with an efficient delivery system for treating chronic hepatitis B (CHB), and explore combined RNA interference (RNAi) and immune modulatory modalities for better vi...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Wenjing Zai, Min Yang, Kuan Jiang, Juan Guan, Huijing Wang, Kongying Hu, Chao Huang, Jieliang Chen, Wei Fu, Changyou Zhan, Zhenghong Yuan
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Publishing Group 2024-06-01
Rangatū:Signal Transduction and Targeted Therapy
Urunga tuihono:https://doi.org/10.1038/s41392-024-01871-8
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