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Thromboxane A(2) receptor stimulation promotes closure of the rat ductus arteriosus through enhancing neointima formation.

Ductus arteriosus (DA) closure follows constriction and remodeling of the entire vessel wall. Patent ductus arteriosus occurs when the DA does not close after birth, and this condition is currently treated using cyclooxygenase inhibitors. However, the efficacy of cyclooxygenase inhibitors is often l...

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Principais autores: Tomohiro Yokota, Ryosuke Shiraishi, Takashi Aida, Kenji Iwai, Norika Mengchia Liu, Utako Yokoyama, Susumu Minamisawa
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC3988076?pdf=render
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