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Transcriptome Analysis Reveals Differential Gene Expression between the Closing Ductus Arteriosus and the Patent Ductus Arteriosus in Humans

The ductus arteriosus (DA) immediately starts closing after birth. This dynamic process involves DA-specific properties, including highly differentiated smooth muscle, sparse elastic fibers, and intimal thickening (IT). Although several studies have demonstrated DA-specific gene expressions using an...

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Principais autores: Junichi Saito, Tomoyuki Kojima, Shota Tanifuji, Yuko Kato, Sayuki Oka, Yasuhiro Ichikawa, Etsuko Miyagi, Tsuyoshi Tachibana, Toshihide Asou, Utako Yokoyama
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-04-01
Serier:Journal of Cardiovascular Development and Disease
Fag:
ductus arteriosus
neointima
tunica media
congenital heart disease
transcriptome
neural crest
Online adgang:https://www.mdpi.com/2308-3425/8/4/45
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