Calpain-6 deficiency promotes skeletal muscle development and regeneration.
Calpains are Ca(2+)-dependent modulator Cys proteases that have a variety of functions in almost all eukaryotes. There are more than 10 well-conserved mammalian calpains, among which eutherian calpain-6 (CAPN6) is unique in that it has amino acid substitutions at the active-site Cys residue (to Lys...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2013-01-01
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| Серии: | PLoS Genetics |
| Online-ссылка: | http://europepmc.org/articles/PMC3731218?pdf=render |
| Метки: |
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