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Dynamics of T-cell Responses Following COVID-19 mRNA Vaccination and Breakthrough Infection in Older Adults

Introduction: While older adults generally mount weaker antibody responses to a primary COVID-19 vaccine series, T-cell responses remain less well characterized in this population. We compared SARS-CoV-2 spike-specific T-cell responses after 2- and 3-dose COVID-19 mRNA vaccination and subsequent br...

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Hoofdauteurs: Sneha Datwani, Rebecca Kalikawe, Francis Mwimanzi, Sarah Speckmaier, Richard Liang, Yurou Sang, Rachel Waterworth, Fatima Yaseen, Hope Lapointe, Evan Barad, Mari DeMarco, Daniel Holmes, Janet Simons, Julio Montaner, Marc Romney, Zabrina Brumme, Mark Brockman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Case Western Reserve University 2023-11-01
Reeks:Pathogens and Immunity
Onderwerpen:
COVID-19
mRNA vaccines
cellular immune response
older adults
activation-induced marker assay
Online toegang:https://www.paijournal.com/index.php/paijournal/article/view/613
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