Rapamycin reduces peritendinous fibrosis but has a limited effect on intratendinous healing in a rodent Achilles tendon injury model

Abstract Tendon injuries are common, affecting both athletes and the general population. Healing is often poor, with deposition of fibrotic, disorganised scar-like tissue leading to continued pain, dysfunction and reinjury. The pathogeneses of many fibrotic diseases, including tendinopathies, are in...

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Detalhes bibliográficos

Principais autores:	Neil Marr, Danae E. Zamboulis, Ross E. Beaumont, Zofia J. Tatarczyk, Marianne Pultar, Yu-Mei Chang, Richard J. Piercy, Richard Meeson, Mandy J. Peffers, John C. W. Hildyard, Chavaunne T. Thorpe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-03-01
coleção:	Scientific Reports
Assuntos:	Tendon Interfascicular matrix Rapamycin mTOR Achilles tendon Tendinopathy
Acesso em linha:	https://doi.org/10.1038/s41598-026-45606-x
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