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Determination of qPCR reference genes suitable for normalizing gene expression in a novel model of Duchenne muscular dystrophy, the D2-mdx mouse.

Duchenne muscular dystrophy (DMD) is a X-linked neuromuscular disorder arising from mutations in the dystrophin gene, leading to a progressive muscle wasting and disability. Currently there is no universal therapy, and there is thus a strong interest in preclinical studies for finding novel treatmen...

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Principais autores: Brigida Boccanegra, Roberta Lenti, Paola Mantuano, Elena Conte, Lisamaura Tulimiero, Richard J Piercy, Ornella Cappellari, John C W Hildyard, Annamaria De Luca
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0310714
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