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Single-Cell Analysis of ADSC Interactions with Fibroblasts and Endothelial Cells in Scleroderma Skin

Adipose-derived stem cells (ADSCs) as part of autologous fat grafting have anti-fibrotic and anti-inflammatory effects, but the exact mechanisms of action remain unknown. By simulating the interaction of ADSCs with fibroblasts and endothelial cells (EC) from scleroderma (SSc) skin in silico, we aim...

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Principais autores: Marvin L. Frommer, Benjamin J. Langridge, Laura Awad, Sara Jasionowska, Christopher P. Denton, David J. Abraham, Jeries Abu-Hanna, Peter E. M. Butler
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-07-01
Serier:Cells
Fag:
single-cell RNA sequencing
scleroderma
skin fibrosis
autologous fat grafting
adipose-derived stem cells
ADSC
Online adgang:https://www.mdpi.com/2073-4409/12/13/1784
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