Mechanistic insights into transposon cleavage and integration by TnsB of ShCAST system

Summary: The type V-K CRISPR-associated transposons (CASTs) allow RNA-guided DNA integration and have great potential as a programmable site-specific gene insertion tool. Although all core components have been independently characterized structurally, the mechanism of how the transposase TnsB associ...

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Autori principali:	Ting Zeng, Jie Yin, Ziwen Liu, Zhaoxing Li, Yu Zhang, Yang Lv, Mei-Ling Lu, Min Luo, Meirong Chen, Yibei Xiao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2023-07-01
Serie:	Cell Reports
Soggetti:	CP: Molecular biology CP: Microbiology
Accesso online:	http://www.sciencedirect.com/science/article/pii/S221112472300709X
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