Positional Cloning of cobblestone, a Mouse Mutant Showing Major Defects in Brain Development, Identifies Ift88 as a Candidate Gene
The ENU-induced cobblestone (cbs) mouse mutant exhibits severe defects in fore- and midbrain development. Via genomic mapping, the causative mutation for the cbs-phenotype has previously been located on chromosome 14 in the proximity of the gene Ift88 (Intraflagellar transport, 88 kDa). The Ift88 pr...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Appalachian State University Dept of Psychology
2010-03-01
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| Colecção: | Impulse: The Premier Undergraduate Neuroscience Journal |
| Assuntos: | |
| Acesso em linha: | http://impulse.appstate.edu/sites/impulse.appstate.edu/files/2010EvsyukovFinal2MAR10.pdf |
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