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Differential Toxicity of Antibodies to the Prion Protein.

Antibodies against the prion protein PrPC can antagonize prion replication and neuroinvasion, and therefore hold promise as possible therapeutics against prion diseases. However, the safety profile of such antibodies is controversial. It was originally reported that the monoclonal antibody D13 exhib...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Regina R Reimann, Tiziana Sonati, Simone Hornemann, Uli S Herrmann, Michael Arand, Simon Hawke, Adriano Aguzzi
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2016-01-01
Цуврал:PLoS Pathogens
Онлайн хандалт:http://europepmc.org/articles/PMC4731068?pdf=render
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