Markedly increased secretion of VLDL triglycerides induced by gene transfer of apolipoprotein E isoforms in apoE-deficient mice

Apolipoprotein E (apoE) plays a key role in the receptor-mediated uptake of lipoproteins by the liver and therefore in regulating plasma levels of lipoproteins. ApoE may also facilitate hepatic secretion of very low density lipoprotein (VLDL) triglyceride (TG). We directly tested the hypothesis that...

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Bibliografische Detailangaben

Hauptverfasser:	Kazuhisa Tsukamoto, Cyrille Maugeais, Jane M. Glick, Daniel J. Rader
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2000-02-01
Schriftenreihe:	Journal of Lipid Research
Schlagworte:	lipoprotein metabolism triglycerides apolipoprotein E gene transfer
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0022227520320599
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