Protocol to perform fragment screening using NMR spectroscopy
Summary: Fragment-based drug design plays an important role in drug discovery. Protein-observed NMR experiments with isotopically labeled samples are used to probe target-ligand interactions and map the ligand-binding sites. Here, we present a protocol to perform fragment screening using NMR spectro...
Furkejuvvon:
| Váldodahkkit: | , |
|---|---|
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Elsevier
2024-09-01
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| Ráidu: | STAR Protocols |
| Fáttát: | |
| Liŋkkat: | http://www.sciencedirect.com/science/article/pii/S266616672400443X |
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