Fusion of tethered membranes can be driven by Sec18/NSF and Sec17/αSNAP without HOPS
Yeast vacuolar membrane fusion has been reconstituted with R, Qa, Qb, and Qc-family SNAREs, Sec17/αSNAP, Sec18/NSF, and the hexameric HOPS complex. HOPS tethers membranes and catalyzes SNARE assembly into RQaQbQc trans-complexes which zipper through their SNARE domains to promote fusion. Previously,...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications Ltd
2021-10-01
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| Col·lecció: | eLife |
| Matèries: | |
| Accés en línia: | https://elifesciences.org/articles/73240 |
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