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Fusion of tethered membranes can be driven by Sec18/NSF and Sec17/αSNAP without HOPS

Yeast vacuolar membrane fusion has been reconstituted with R, Qa, Qb, and Qc-family SNAREs, Sec17/αSNAP, Sec18/NSF, and the hexameric HOPS complex. HOPS tethers membranes and catalyzes SNARE assembly into RQaQbQc trans-complexes which zipper through their SNARE domains to promote fusion. Previously,...

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Bibliográfalaš dieđut
Váldodahkkit: Hongki Song, William T Wickner
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: eLife Sciences Publications Ltd 2021-10-01
Ráidu:eLife
Fáttát:
Liŋkkat:https://elifesciences.org/articles/73240
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