Evaluating transportability of in vitro cellular models to in vivo human phenotypes using gene perturbation data
Abstract Gene perturbation screens (e.g. CRISPR-Cas9) assess the impact of gene disruption on in-vitro cellular phenotypes (e.g., proliferation, anti-viral response). In-vitro experiments can be useful models for in-vivo (organismal) phenotypes (e.g., immune cell anti-viral response and infectious d...
שמור ב:
| Principais autores: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Portfolio
2025-12-01
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| סדרה: | Nature Communications |
| גישה מקוונת: | https://doi.org/10.1038/s41467-025-67199-1 |
| תגים: |
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