COLEC12 tumor-associated macrophages orchestrate lenvatinib resistance and cancer stemness in hepatocellular carcinoma via paracrine NRG1-HER2/HER3 signaling

Background/Aims Lenvatinib resistance remains a critical barrier in advanced hepatocellular carcinoma (HCC) therapy. However, the underlying mechanisms and strategies for reversing resistance remain incompletely understood. Methods Integrated transcriptomics of lenvatinib-resistant patient tumors an...

Descripció completa

Dades bibliogràfiques

Autors principals:	Jianxing Zhang, Liang Qiao, Zongfeng Wu, Dinglan Zuo, Shanshan Huang, Shaoru Liu, Zhenkun Huang, Yi Zeng, Yu Li, Yichuan Yuan, Chenwei Wang, Wei He, Jiliang Qiu, Yunfei Yuan, Yi Niu, Binkui Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Korean Association for the Study of the Liver 2026-04-01
Col·lecció:	Clinical and Molecular Hepatology
Matèries:	hepatocellular carcinoma lenvatinib resistance colec12 nrg1 cancer stemness
Accés en línia:	http://e-cmh.org/upload/pdf/cmh-2025-1059.pdf
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!