Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance

Abstract Cancer stem cells are essential for initiation and therapy resistance of many cancers, including acute myeloid leukemias (AML). Here, we apply functional genomic profiling to diverse human leukemias, including high-risk MLL- and NUP98-rearranged specimens, using label tracing in vivo. Human...

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Үндсэн зохиолчид:	Sumiko Takao, Victor Morell, Masahiro Uni, Alicia Slavit, Sophia Rha, Shuyuan Cheng, Laura K. Schmalbrock, Fiona C. Brown, Sergi Beneyto-Calabuig, Richard P. Koche, Lars Velten, Alex Kentsis
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-04-01
Цуврал:	Nature Communications
Онлайн хандалт:	https://doi.org/10.1038/s41467-025-58370-9
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!