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Complement activation during cardiopulmonary bypass and association with clinical outcomes

Abstract In this prospective, single‐centre observational study of 30 patients undergoing cardiopulmonary bypass (CPB), the effect of unfractionated heparin (UFH), CPB surgery and protamine sulphate on complement and on post‐operative blood loss were assessed. Although C3 and C4 levels decreased sig...

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Principais autores: Rengina Kefalogianni, Farah Kamani, Mihaela Gaspar, TC Aw, Jackie Donovan, Mike Laffan, Matthew C. Pickering, Deepa J. Arachchillage
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-02-01
coleção:eJHaem
Assuntos:
anaphylatoxins
bleeding
cardiopulmonary bypass
complement
heparin
protamine sulphate
Acesso em linha:https://doi.org/10.1002/jha2.371
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