SOX2 confers tumour permissiveness in a specific skin progenitor population

Abstract The continuous renewal of the skin relies on stem and progenitor cells, yet their differential susceptibility to oncogenic mutations in cutaneous squamous cell carcinoma (cSCC) remains unclear. Rapid cSCC develops in melanoma patients on BRAF inhibitors due to paradoxical MAPK activation. T...

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Hlavní autoři:	Patricia P. Centeno, Christopher Chester, Georgios Kanellos, Catriona A. Ford, Patrizia Cammareri, Gareth J. Inman, Thomas Jamieson, Rachel A. Ridgway, Richard Marais, Andrew D. Campbell, Owen J. Sansom
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-01-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-025-66251-4
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!