Preclinical Evaluation of a New Format of ⁶⁸Ga- and ¹¹¹In-Labeled Affibody Molecule Z_IGF-1R:4551 for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT

The Insulin-like growth factor-1 receptor (IGF-1R) is a molecular target for several monoclonal antibodies undergoing clinical evaluation as anticancer therapeutics. The non-invasive detection of IGF-1R expression in tumors might enable stratification of patients for specific treatment and improve t...

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Egile Nagusiak:	Yongsheng Liu, Shengze Yu, Tianqi Xu, Vitalina Bodenko, Anna Orlova, Maryam Oroujeni, Sara S. Rinne, Vladimir Tolmachev, Anzhelika Vorobyeva, Torbjörn Gräslund
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2022-07-01
Saila:	Pharmaceutics
Gaiak:	IGF-1R PET SPECT gallium-68 indium-111 affibody molecules
Sarrera elektronikoa:	https://www.mdpi.com/1999-4923/14/7/1475
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