GRB2 is a BECN1 interacting protein that regulates autophagy
Abstract GRB2 is an adaptor protein of HER2 (and several other tyrosine kinases), which we identified as a novel BECN1 (Beclin 1) interacting partner. GRB2 co-immunoprecipitated with BECN1 in several breast cancer cell lines and regulates autophagy through a mechanism involving the modulation of the...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2024-01-01
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| Schriftenreihe: | Cell Death and Disease |
| Online-Zugang: | https://doi.org/10.1038/s41419-023-06387-7 |
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