Icatibant Acts as a Balanced Ligand of MRGPRX2 in Human Skin Mast Cells
MRGPRX2 (Mas-related G protein-coupled receptor member X2) is implicated in mast cell (MC)-driven disorders due to its ability to bind diverse ligands, which may be G-protein-biased or balanced, with the latter activating both G-proteins and the β-arrestin pathway. Icatibant, a peptide drug, produce...
Gardado en:
| Principais autores: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2025-08-01
|
| Series: | Biomolecules |
| Assuntos: | |
| Acceso en liña: | https://www.mdpi.com/2218-273X/15/9/1224 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|