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Identification of Novel Piperidine and Pyrrolidine Derivatives as Potent Inhibitors of Pancreatic Lipase-Based Molecular Docking and In Vitro Testing

Obesity is a major global health concern associated with increased risks of chronic diseases and mortality. Inhibiting pancreatic lipase, a key enzyme in dietary fat absorption, presents a promising therapeutic approach. This study aimed to evaluate the inhibitory potential of piperidine derivatives...

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Principais autores: Acharaporn Duangjai, Kwanruthai Tadpetch, Vatcharin Rukachaisirikul, Chutima S. Vaddhanaphuti, Maleeruk Utsintong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-08-01
Serier:Scientia Pharmaceutica
Fag:
pancreatic lipase
molecular docking
anti-obesity
piperidine
pyrrolidine
Online adgang:https://www.mdpi.com/2218-0532/93/3/43
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