Acute deletion of TET enzymes results in aneuploidy in mouse embryonic stem cells through decreased expression of Khdc3

Inducible disruption of TET dioxygenases in mouse embryonic stem cells results in chromosome mis-segregation and aneuploidies, due to Khdc3 downregulation suggesting a role for TET enzymes and DNA methylation patterns in maintaining genome stability.

Bibliografski detalji

Glavni autori:	Romain O. Georges, Hugo Sepulveda, J. Carlos Angel, Eric Johnson, Susan Palomino, Roberta B. Nowak, Arshad Desai, Isaac F. López-Moyado, Anjana Rao
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2022-10-01
Serija:	Nature Communications
Online pristup:	https://doi.org/10.1038/s41467-022-33742-7
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